ADRA-01

designed by adrafül labs inc.

a proprietary stack optimized for
mental clarity and cognitive
longevity.

ADRA-01

designed by adrafül labs inc.

a proprietary stack optimized for
mental clarity and cognitive
longevity.

[ formulation release ] december 2023

the first proprietary blend designed specifically for the productive class.

sustained energy

no crash

more focus

no jitters

more energy, less caffeine.

the first proprietary blend designed specifically for the productive class.

motivation & wakefulness

task-based cognitive enhancement

mental clarity

executive function

more energy, less caffeine.

motivation & wakefulness:

caffeine

[ C8H10N4O2 ]

+

l-theanine

[ C7H14N2O3 ]

increase motivation & alertness

we combine caffeine with l-theanine in a 1:2 ratio based on extensive literature that suggests a strong synergistic effect in boosting cognitive performance[1][2].

caffeine is an adenosine receptor antagonist (promoting wakefulness) and l-theanine has been documented to reduce the anxiety-related side-effects of caffeine.

mucuna pruriens  [ C9H11NO4 ]

increase dopamine availability

we combine caffeine with l-theanine in a 1:2 ratio based on extensive literature that suggests a strong synergistic effect in boosting cognitive performance.


caffeine is an adenosine receptor antagonist (promoting wakefulness) and l-theanine has been documented to reduce the anxiety-related side-effects of caffeine.

motivation & wakefulness:

caffeine

[ C8H10N4O2 ]

+

l-theanine

[ C7H14N2O3 ]

increase motivation & alertness

we combine caffeine with l-theanine in a 1:2 ratio based on extensive literature that suggests a strong synergistic effect in boosting cognitive performance[1][2].

caffeine is an adenosine receptor antagonist (promoting wakefulness) and l-theanine has been documented to reduce the anxiety-related side-effects of caffeine.

mucuna pruriens  [ C9H11NO4 ]

increase dopamine availability

we combine caffeine with l-theanine in a 1:2 ratio based on extensive literature that suggests a strong synergistic effect in boosting cognitive performance.


caffeine is an adenosine receptor antagonist (promoting wakefulness) and l-theanine has been documented to reduce the anxiety-related side-effects of caffeine.

task-based cognitive enhancement:

alpha-GPC  [ C8H20NO6P ]

stimulate acetylcholine production

α-GPC is a highly bioavailable form of choline[3], which can be used in the synthesis of acetylcholine and promote neurotransmission. α-GPC has been shown to lead to statistically significant improvements in learning and memory tasks[4] and may increase performance in other cognitively demanding tasks (like mental math[5] ) and in physical performance[6].

α-GPC provides a source for acetylcholine that downstream components of ADRA-01 exploit for out-of-sample improvements in cognitive performance.

uridine monophosphate  [ C9H13N2O9P ]

improve task-based cognitive function & verbal fluency

uridine is a naturally occurring (in the liver[7]) nucleotide base that acts as a monomer in RNA and is used to promote cellular membrane genesis. uridine’s involvement in the CDP-choline pathway leads to the formation of phosphatidylethanolamine, a phospholipid that plays a key role in neurotransmission[8]. we include UMP for its clear intellectual-

enhancing effects as well as its theorized ability to improve verbal fluency[9]. studies have shown that when taken in conjunction with a source of DHA and choline (provided by α-GPC), UMP can lead to significant cognitive enhancement in animals[10].

task-based cognitive enhancement:

alpha-GPC  [ C8H20NO6P ]

stimulate acetylcholine production

α-GPC is a highly bioavailable form of choline[3], which can be used in the synthesis of acetylcholine and promote neurotransmission. α-GPC has been shown to lead to statistically significant improvements in learning and memory tasks[4] and may increase performance in other cognitively demanding tasks (like mental math[5]) and in physical performance[6].

α-GPC provides a source for acetylcholine that downstream components of ADRA-01 exploit for out-of-sample improvements in cognitive performance.

uridine monophosphate  [ C9H13N2O9P ]

improve task-based cognitive function & verbal fluency

uridine is a naturally occurring (in the liver[7]) nucleotide base that acts as a monomer in RNA and is used to promote cellular membrane genesis. uridine’s involvement in the CDP-choline pathway leads to the formation of phosphatidylethanolamine, a phospholipid that plays a key role in neurotransmission[8]. we include UMP for its clear intellectual-

enhancing effects as well as its theorized ability to improve verbal fluency[9]. studies have shown that when taken in conjunction with a source of DHA and choline (provided by α-GPC), UMP can lead to significant cognitive enhancement in animals[10].

mental clarity:

PQQ  [ C14H6N2O8 ]

Pyrroloquinoline quinone is an antioxidant that supports mitochondrial biogenesis[11], which supports youthful cell function throughout the entire body. Research suggests that PQQ can increase attention, information processing, and short-term memory across various age groups[12][13]. Individuals over the age of 40 may experience even greater improvements in cognitive performance due to the natural decline in mitochondrial function that comes along with age.

We include PQQ for its attention-improving effects and ability to direct focus to particular tasks for extended periods of time.

mental clarity:

PQQ  [ C14H6N2O8 ]

Pyrroloquinoline quinone is an antioxidant that supports mitochondrial biogenesis[11], which supports youthful cell function throughout the entire body. Research suggests that PQQ can increase attention, information processing, and short-term memory across various age groups[12][13]. Individuals over the age of 40 may experience even greater improvements in cognitive performance due to the natural decline in mitochondrial function that comes along with age.

We include PQQ for its attention-improving effects and ability to direct focus to particular tasks for extended periods of time.

executive function:

agmatine  [ C5H14N4 ]

agmatine is most commonly used for its neuroprotective effects in treatments against central nervous system (CNS) disorders like Alzheimer’s Disease. however, we include it in ADRA-01 primarily because of its potential for activation of the alpha-2 adranergic receptor (α2A) which can inhibit the release of noradrenaline and improve metacognition[18].

executive function:

agmatine  [ C5H14N4 ]

agmatine is most commonly used for its neuroprotective effects in treatments against central nervous system (CNS) disorders like Alzheimer’s Disease. however, we include it in ADRA-01 primarily because of its potential for activation of the alpha-2 adranergic receptor (α2A) which can inhibit the release of noradrenaline and improve metacognition[18].

citations: